High CA – 125 in Patients with Endometrioma

Ovarian endometrioma associated with very high serum CA-125 levels.

CA-125 is a 220-kD cell surface glycoprotein present in over 80% of non-mucinous epithelial ovarian carcinomas and it occurs in the serum of healthy males and females at low concentrations (< 35 U/mL). Serum CA-125 concentration may also be moderately elevated in several benign conditions, such as pelvic inflammatory disease, uterine fibroids, pregnancy, spontaneous abortion with chromosomal ab...

extra-ordinary high ca-125 and ca19-9 serum levels in an ovarian endometrioma: case report

endometriosis is an estrogen dependent disease. levels of cancer antigen-125 are significantly higher in women with moderate to severe endometriosis. however, patients with unruptured endometriosis rarely have serum ca-125 levels more than 1000 u/ml. this case report presents a diffuse, unruptured ovarian endometrioma in a 29- year-old woman, leading to an extraordinary high serum ca-125 and ca...

Ruptured Endometrioma Presenting as Acute Abdomen with Highly Raised Serum CA-125 Levels: A Case Report

A 35 yr old lady, para 2, living 2, with 2 previous caesarean sec­ tions, presented with the features of acute abdomen. The clinical and laboratory evaluations revealed a bilateral ovarian mass with solid and cystic components, with raised serum CA­125 levels and raised ESR. The differential diagnosis included abdominal or genital tuberculosis, secondary carcinoma of the ovaries and endometriom...

Florid Adnexal Polypoid Endometriosis Associated with Very High Serum Ca - 125 Levels Mimicking Ovarian Malignancy

We report a case of florid polypoid endometriosis presenting with advanced bulky disease in pelvis with serum CA – 125 levels of 7844U/ml. The extent of tumor, CT scan findings, elevated serum CA – 125 levels were suggestive of ovarian malignancy. Histopathology demonstrated endometrial glands and stroma. Glands were neither crowded nor complex and were separated by a fibromatous stroma that co...

"High-dose hook effect" with the Centocor CA 125 assay.